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To understand about embryonic stem cell.
"To realize the promise of novel cell-based therapies for such pervasive and debilitating diseases, scientists must be able to manipulate stem cells so that they possess the necessary characteristics for successful differentiation, transplantation, and engraftment. The following is a list of steps in successful cell-based treatments that scientists will have to learn to control to bring such treatments to the clinic. To be useful for transplant purposes, stem cells must be reproducibly made to:
Stem cell research is a part of biomedical science that has the potential to cure diseases and defects, create organs for patients needing transplants, regenerate axons in spinal cord injuries, and create new treatments, drugs, and immunizations.
Figure 1.1. How Human Embryonic Stem Cells are Derived.
The fact that the cells may come from embryos is not an objection, because the embryos are going to die anyway." -- Stephen Hawking The phrase “stem cell” calls to mind images of controversy: Pro-life picketers outside abortion and in-vitro fertilization clinics, patients with chronic disabilities waiting on a cure, scientists in a lab experimenting with a petri dish....
To summarize, stem cells offer exciting promise for future therapies, but significant technical hurdles remain that will only be overcome through years of intensive research."
Journal articles on embryonic stem cell research
In the decades after, global initiatives into stem cell research have produced large strides in scientific understanding and use in medical treatments of disease and injuries.
More scientific research, however, needs to go into more possible solutions, to find a more humane method of treating these diseases that pleases both sides of the stem cell research debate, for the soluti...
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Unfortunately, Embryonic Stem Cell Research has a dark side.
* Editor's note: Papers published since this writing report defined culture conditions for human embryonic stem cells. See Ludwig et al., Nat. Biotech 24: 185–187, 2006; and Lu et al., PNAS 103:5688–5693, 2006.08.14.
The discoveries of embryonic stem, ES, cells in 1998 by James A.
Kaufman, MD., Ph.D., who stated: “It is important to recognize that human embryonic stem cells all come from embryos created in excess by fertility clinics....
I believe that, stem cell research has many more pros than cons.
Prentice in the opening paragraph of his article, “The Real Promise of Stem Cell Research.” “Embryonic stem cells are cells obtained from an embryo in the blastula phase, when they are still only a few days old.
Bush banned the further funding of embryonic stem cell research.
Prentice is arguing against using real-life embryos and would rather see the research be done on fake stem cells that were made using synthetic materials.
The 1900s brought upon more research in using stem cells.
The ability of ES cells to develop into all cell types of the body has fascinated scientists for years, yet remarkably little is known about factors that make one cell pluripotent and another more restricted in its developmental potential. The transcription factor Oct4 has been used as a key marker for ES cells and for the pluripotent cells of the intact embryo, and its expression must be maintained at a critical level for ES cells to remain undifferentiated. The Oct4 protein itself, however, is insufficient to maintain ES cells in the undifferentiated state. Recently, two groups identified another transcription factor, Nanog, that is essential for the maintenance of the undifferentiated state of mouse ES cells., The expression of Nanog decreased rapidly as mouse ES cells differentiated, and when its expression level was maintained by a constitutive promoter, mouse ES cells could remain undifferentiated and proliferate in the absence of either LIF or BMP in serum-free medium. Nanog is also expressed in human ES cells, though at a much lower level compared to that of Oct4, and its function in human ES cells has yet to be examined.
Notably, embryonic stem cells are harvested in a strange way....
This point causes much debate and anger of those opposed to stem cell research but they ultimately look at the process and not the form or result of it.
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